![]() “We acquired DCTclock because we view it as a new gold standard. Because of the scalable nature of software, these digitized cognitive functional assessments greatly increase accessibility to the population and lower the cost as well as the burden on the patient,” said David Bates, Linus Health CEO. Digital tools enable not only incredible sensitivity but are also a measure of brain function, which is arguably more clinically important than even some molecular markers. “Early detection is critical for advancing the study and treatment of cognitive impairment. Moreover, the DCTclock outperformed the PACC at differentiating clinically normal individuals with amyloid plaque deposits from those without. The study found the digital assessment to have significant correlation with PET imaging scans that can detect evidence of amyloid plaques in asymptomatic individuals. In the MGH study, more than 300 participants from the Harvard Aging Brain Study were given the DCTclock test alongside the Preclinical Alzheimer’s Clinical Composite (PACC) - a 30-minute battery of pen-and-paper based cognitive tests - and PET brain imaging scans. Randall Davis of Massachusetts Institute of Technology, who invented and developed the original Digital Clock Drawing Test beginning in 2005. Dana Penney of Beth Israel Lahey Health and Dr. ![]() Linus Health acquired the DCTclock test in 2020 the test is based on the seminal work of Digital Cognition Technology (DCT) founders Dr. The Linus Health DCTclock is a new approach to the standard Clock Drawing Test, as a rapid, sensitive tool that closely correlates with test results from costly brain imaging procedures for screening a population with no apparent symptoms. However, the positron emission tomography (PET) scans that can identify the biomarkers required for Alzheimer’s detection are expensive and often inaccessible to patients in many clinical settings. Cognitive testing that includes pen-and-paper tests such as the Clock Drawing Test, is the 50-year-old standard, but it’s time consuming and has limited sensitivity to detect the onset of the disease before greater impact on memory, language, or visuospatial problems. Early detection of cognitive impairment, especially in the pre-symptomatic stage, is a key step towards enabling disease modification-from implementing timely lifestyle changes to discovering new disease-modifying targets to expand currently limited treatment options. The Linus Health Inc DCTclock™ digital clock-drawing test is a Food and Drug Administration (FDA) registered Class II medical device for cognitive assessment that can be easily administered at a lower cost and time burden than traditional methods.Īmyloid beta plaques associated with Alzheimer’s disease can appear in the brain as early as 15 to 20 years before clinical symptoms manifest. In this case, the individual would benefit from a comprehensive neurological examination.BOSTON-( BUSINESS WIRE)-A newly published study in Neurology by researchers at the Massachusetts General Hospital (MGH) revealed that DCTclock™, a digital version of the classic Clock Drawing Test (CDT), was effective in identifying the beginnings of Alzheimer’s disease pathology in cognitively normal individuals, those with no outward symptoms of dementia. left hemineglect) suggests that there is a right parietal cortical lesion. In the example ( figure 4) showing hemineglect, the absence of numbers on the left (i.e. Individuals with an autoimmune encephalitis may also present with rapid cognitive impairment and deficits on clock drawing. ![]() Neglect can be further divided into motor and sensory components, extinction, anosognosia (denial of illness), and anosodiaphoria (minimization of illness). Patients with right-sided lesions typically neglect the left hemispace. Other areas, such as the thalamus and the basal ganglia, can also be involved. It is most common after lesions of right parietal lobe or right frontal lobe. ![]() Neglect can commonly be seen in individuals with stroke. In this case, the clock-drawing test can be used to reveal neglect, but is not diagnostic. The usual striking example is when a clock drawing has all the numbers on one half of the clock but not the other half. In individuals with spatial deficits, there may be crowding of numbers and/or obvious impairments in the layout of the clock.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |